Clinical Epidemiology & Biostatistics


Lehana Thabane

BSc (Lesotho), MSc (Sheffield), PhD (Western)

Professor/Associate Chair, Department of Clinical Epidemiology & Biostatistics

Director, Biostatistics Unit, Centre for Evaluation of Medicine

Senior Scientist, Population Health Research Institute (PHRI), Hamilton Health Sciences, McMaster University

Director of Biostatistics, System-Linked Research Unit, SLRU

905.522.1155 x 33720
905.308.7386
thabanl@mcmaster.ca

Centre for Evaluation of Medicines
105 Main Street East, Level P1
Hamilton, ON L8N 1G6

For Biostatistics Unit information click here

Project Assistant: Rosemary Oliveira
905.522.1155 x 34905
905.308.7386
rolivei@mcmaster.ca

For more information on Dr. Thabane click here

Academic Interests

Dr. Thabane is a research methodologist with research interests in the development and application of statistical methods health research. He collaborates with researchers in cardiology, internal medicine, nephrology, HIV-AIDS, evidence-based medicine and health technology assessment. He provides statistical leadership in studies in various areas of population health research, clinical research, health services and outcomes research. As research methodologist, his research interests cover a wide spectrum of research areas including clinical trials, research ethics, and conjoint analysis of patient preferences for colorectal cancer screening. The applications of Bayesian hierarchical methods to model medical data, systematic reviews and meta-analysis of RCT's using both Bayesian and classical approaches.

Current HRM Graduate Students
Sameer Parpia, PhD in Biostatistics
Junhui Ma, PhD in Biostatistics
Rong (Rachel) Chu, PhD in Biostatistics
Ji (Emmy) Cheng PhD in Biostatistics
Courtney Kennedy, PhD in HRM - Clinical Epidemiology
Chenglin Ye, PhD in Biostatistics
Lawrence Mbuagbaw, PhD in HRM - Clinical Epidemiology
Victoria Borg Debono, MSc
Shiyuan (William) Zhang, MSc
Sarah Daisy Kosa, MSc
Jeff Muir, MSc

Current Math & Stats Graduate Students
Thuva Vanniyasingam, MSc

Recent HRM Graduate Students
Robert Hopkins, PhD in Biostatistics, currently Biostatistician, PATH, McMaster University
Janice Pogue, PhD in Biostatistics, currently Statistical Manager, Population Health Institute
Kristian Thorlund, Phd in Biostatistics, currently Research Officer, Vancouver Hospital
Lisa-Ann Fraser, MSc
Juan Guzman, MSc
Luiz Garrido-Olivares, MSc
George Ioannidis, PhD
Adewope Odueyungbo, PhD

Recent Math & Stats Graduate Students
Ji (Emmy) Cheng, MSc 2007, currently Research Associate, Biostatistics Unit, St. Joseph's Healthcare Hamilton and part-time student HRM PhD in Biostatistics
Jinhui Ma, MSc 2007, currently student in HRM PhD in Biostatistics
Weiwei Xiong, MSc 2008, currently Research Assistant, St. Joseph's Healthcare Hamilton
Jennifer Liu, MSc 2009, currently Data Analyst, Cancer Care Ontario
Chenglin Ye, MSc 2009, currently PhD  HRM student
Yan Yun Liu, MSc 2010, currently Data Analyst ECP: Evidence-based Practice Center
Yu Qing Bai, MSc 2010, currently Research Officer, University  of Toronto
Xu Jian-Yi, MSc 2010, currently Statistical Associate, Alberta Health Services

Selected Publications

  1. Mbuagbaw LCE*, Thabane L, Ongolo-Zogo P, Lang Trudie. The challenges and opportunities of conducting a clinical trial in a low resource setting: the case of the Cameroon mobile phone SMS (CAMPS) trial, an investigator initiated trial. Trials 2011; 12:145.
  2. Holbrook A, Pullenayegum EM,Thabane L, Troyan S, Foster G, Keshavjee K, Chan D, Dolovich L, Gerstein H, Demers C, Curnew G. Shared ElectronicVascular Risk Decision Support in Primary Care: Computerization of Medical Practices for the Enhancement of Therapeutic Effectiveness (COMPETE III ) RandomizedTrial. International Achieves of Medicine2011 Oct 24; 171(19):1736-44.
  3. Ma J*, Akhtar A, Dolovich LR, Thabane L. Imputation strategies for missing binary outcomes in cluster randomized trials. BMC Medical Research Methodology 2011 Feb 16;11:18.
  4. Thabane L, Wells G, Cook R, Platt R, Pogue J*, Pullenayegum E, Matthews D, McCready T, Devereaux PJ, Cairns JA, Yusuf S. Canadian-led capacity-building in biostatistics and methodology in cardiovascular and diabetes trials: the CANNeCTIN Biostatistics and Methodological Innovation Working Group. Trials 2011 Feb 18;12(1):48.
  5. Ye C*, Giangregorio L, Holbrook A, Pullenayegum EM, Goldsmith CH, Thabane L. Data withdraw in randomized controlled trials: Defining the problem and proposing solutions: a commentary.  Contemporary Clinical Trials 2011 May; 32(3):318-22. Epub 2011 Feb 4.
  6. Thorlund K*, Awad T, Boivin G, Thabane L. Systematic Review of Influenza Resistance to the Neuraminidase Inhibitors. BMC Infect Dis 2011 May 19; 11(1):134 [Epub ahead of print].
  7. Hopkins RB*, Pullenayegum E, Goeree R, Adachi JD, Papaioannou A, Leslie WD, Tarride JE, Thabane L. Estimation of the lifetime risk of hip fracture for women and men in Canada. Osteoporos Int 2011.
  8. Fraser LA*, Voght KN, Adachi JD, Thabane L. Fracture risk associated with continuation versus discontinuation of bisphosphonates after 5 years of therapy in patients with primary osteoporosis: a systematic review and meta-analysis. Therapeutics and Clinical Risk Management 2011 May 2011:7(157).
  9. Ma J*, Akhtar A, Dolovich LR, Thabane L. Imputation strategies for missing binary outcomes in cluster randomized trials. BMC Medical Research Methodology 2011 Feb 16; 11(1):18 [Epub ahead of print].
  10. Chu R*, Thabane L, Ma J*, Holbrook A, Pullenayegum EM, Devereaux PJ. Comparing methods to estimate treatment effects on a continuous outcome in multicentre randomized controlled trials: A simulation study. BMC Medical Research Methodology 2011 11:21.

* Graduate student or mentee under my supervision

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